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The Bioseparation Engineering Group deals with different aspects of the isolation and purification
of biomolecules for the pharmaceutical or chemical industry. We are focused on adsorption, filtra-
tion and extraction as separation methods as well as their integration into the production process.
In addition to the experimental approaches we use COMSOL and COSMO-RS for modelling and
simulation.
Bioseparation Engineering
Process development and intensification, particle technology, adsorption, filtration, and extraction
2017 was a particularly successful year for the Biosepa-
ration Engineering Group. The small group can look back
on three completed Ph.D. theses, seven peer-reviewed
papers, and one patent application. In addition, we
launched two new third-party funded projects with various
academic and industrial partners.
In one project, we focus on a multi-scale approach to
better understand a potential-controlled chromatography
for process intensification. In the second project, we
work closely with industry to establish a new sustainable
process for purifying small protective solutes.
New Stationary Phases
Preparative chromatography for the separation of biomolecules. Source: Raphael Lichtecker
New stationary phases are essential in bioseparation
sciences; classical phases are already well developed and
reach their limits. The Bioseparation Engineering Group is
specialized in synthesis and functionalization of magnetic
particles and conductive materials as well as their process
implementation. Making use of magnetism or conductivity
allows for an additional degree of freedom for state-of-
the-art process development.
Projects
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Synthesis, functionalization, and characterization of
magnetic nanoparticles
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New conductive materials for potential-controlled
chromatography